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[1] In addition, mutations of residues around the ligand-binding pockets of fentanyl and morphine, including Y150 3.33 , M153 3.36 , V238 5.42 , I298 6.51 , and H299 6.52 , resulted in attenuated activities toward G protein and -arrestin signaling of both ligands (Figure 4a-b)

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doi:10.1016/j.solener.2011.08.012 Perks S, Robertson S, Haywood A, Glass B (2012) Clozapine repackaged into dose administration aids: a common practice in Australian hospitals