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Additionally, individual differences in the digestive system, such as stomach or intestines conditions, can impact how effectively B12 is absorbed from food or supplements

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Autophagy is a highly conserved lysosomal degradation pathway

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While residing in the nucleus the PDHc is constitutively repressed by a scaffolding component of the mitotic deacetylase complex identified as ELMSAN1 (ELM2SANT domaincontaining scaffolding protein 1)