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By sequestering actin monomers and controlling their polymerization into filaments, TB-500 enables enhanced migration of fibroblasts, endothelial cells, and immune cells to injury sites
The combined effect can lead to an amplified anticoagulant effect, potentially pushing the patient beyond their therapeutic range and increasing the likelihood of hemorrhagic complications (242)
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However, these medications may come with some side effects , including nausea, vomiting, diarrhea, and abdominal discomfort, particularly when starting the treatment