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Furthermore, no well-defined genetic variants were found in GSH, except for single nucleotide polymorphisms (SNPs) in GS, namely rs7265992, rs6060124, rs7260770, rs4911455, rs6088662, and in GPX5, namely rs377514

However, if the stool is simply darker than usual, it could be caused by medications like iron supplements, bismuth subsalicylate (such as Pepto-Bismol), or activated charcoal

7 That said, a mechanism that keeps the stomach fuller for longer warrants caution in people with pre-existing gastroparesis or motility disorders, and it is a theoretical consideration before procedures requiring an empty stomach

For peripheral neuropathies, particularly diabetic neuropathy, local nanoparticle delivery to the dorsal root ganglia or peripheral nerves has shown potential to promote axonal regeneration and reduce oxidative damage [286, 311]

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