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At physiological concentrations, ROS is important to cellular division, but excessive ROS leads to stressed damages to protein, DNA and lipid (Mani et al., 2020)

Generic name: Oral Semaglutide 3mg Tablets 30s Semaglutide belongs to a group of medications known as glucagon-like peptide-1 (GLP-1) receptor agonists and can be taken orally or via an injectable pen

Semaglutide may not be suitable for people with a history of pancreatitis, thyroid cancer, multiple endocrine neoplasia syndrome type 2 (MEN 2), or a known allergy to Semaglutide

doi: 10.3389/fendo.2021.645563 Received 23 December 2020 Accepted 19 April 2021 Published 07 July 2021 Volume 12 - 2021 Edited by Francesco Giorgino, University of Bari Aldo Moro, Italy Reviewed by Bo Ahrn, Lund University, Sweden

KGN cells were maintained in Dulbecco's Modified Eagle Medium (DMEM, Gibco, USA) supplemented with 10% fetal bovine serum (FBS) and 1% penicillin/streptomycin at 37 C within a CO 2 incubator