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But, at the same time, it also prevents useful substances from reaching the brain

Controlled trials reveal that chronic citrulline supplementation lowers peripheral and central systolic pressures, diminishes arterial stiffness indices, and improves skeletal- muscle perfusion during exercise rehabilitation

This botanical drug exhibits anti-inflammatory, antitumor activity, and antimutagenic effects

A third piece of the puzzle involves clearance rather than activation

This may contribute to eye fatigue, difficulty focusing, dizziness, disorientation, reduced peripheral vision, and other symptoms associated with prolonged screen exposure