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Though clinical trials in healthy subjects generally confirm its safety, some adverse effects, including diarrhea, headache, rash, and yellow stool, have been reported at doses ranging from 500 to12,000 mg [234]

Macrophage membrane-coated nanocarriers co-modified by RVG29 and TPP improve brain neuronal mitochondria-targeting and therapeutic efficacy in Alzheimers disease mice

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The STEP 1 extension study found that two-thirds of weight lost during treatment was regained within a year of stopping