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The 2008 Dalmasso et al

17 Recent studies have revealed that partial reprogramming can reverse the epigenetic characteristics of aging without eliminating cells

This is the trial the FDA has been waiting for

[2] A 2025 randomised phase 1 trial in adults with overweight or obesity found that tirzepatide reduced overall appetite, food cravings, tendency to overeat, perceived hunger and reactivity to foods in the environment, while not increasing cognitive restraint