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After the fixation, tissue samples were routinely processed and embedded in paraffin wax from that 5m-thick sections were cut

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Preclinical studies with SAR425899 clearly demonstrated dual receptor agonism in vitro and in preclinical in vivo studies, with a higher potency for the GLP1R than for the glucagon receptor in order to counterbalance the GCGR mediated increase of blood glucose levels through GLP-1 agonism 11,12,13

How often are treatments recommended?+ Treatment frequency is customized to each patient

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