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Trials have shown meaningful weight loss, better sugar control, and fewer heart attacks, which is why semaglutide, liraglutide, dulaglutide, and tirzepatide have now been added to the WHO Model List of Essential Medicines

Despite its effectiveness, many patients find long-term use difficult to tolerate

[DOI] [PMC free article] [PubMed] [Google Scholar] 53.Martins RS, Masood MQ, Mahmud O, Rizvi NA, Sheikh A, Islam N, et al

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Most Common Mounjaro Side Effects & Percentage of People Who Experience Them These symptoms are usually at their worst when you start Mounjaro or increase your dose, but they often become milder over time