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Epigenetic dysregulation in IR Recent studies have suggested that epigenetic modifications such as DNA methylation (DNAm) and histone post-translational modifications (PTM) are implicated in the development of systemic IR
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Gene expression levels were calculated using the 2-Ct method[25] and expressed as relative units (RU) compared to the untreated controls where the level of gene expression was considered to be equal to 1
Abstract Introduction Estrogen deprivation using aromatase inhibitors is one of the standard treatments for postmenopausal women with estrogen receptor (ER)-positive breast cancer
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