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Liquid intake (proper hydration): [6] Which Supplements to Take During GLP-1 Treatment

For example, an increased risk of kidney stones could come from dehydration caused by lack of appetite, rather than an effect of the drug itself

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On the pancreatic cancer question specifically, a study of over 540,000 adults found no support for an increased pancreatic cancer incidence over 7 years following start of GLP-1RA treatment. The authors note that longer follow up is still needed, however, and its important to consider how the use of these drugs has skyrocketed recently