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A comparative study of lixisenatide and exenatide BID as supplemental treatments to metformin revealed a similar reduction in HbA1c, but lixisenatide caused less hypoglycemia, slightly less weight loss, and had a more favorable gastrointestinal tolerance profile after 24 weeks

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Baseline characteristics included a mean age of 48 years, 71% female, 72% White, 14% Asian, 9% Black or African American, and 5% reported as other or unknown