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Here's how the two groups compared on reaching key weight loss milestones: Waist circumference also shrank more with tirzepatide: an average of 18.4 cm (about 7 inches) compared to 13.0 cm (about 5 inches) with semaglutide.[1] "The SURMOUNT-5 head-to-head results demonstrated tirzepatide led to greater weight reduction compared to semaglutide," said Dr

She wound up visiting the hospital four or five times in the space of two weeks, she said