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In parallel, advances in peptide chemistry and structural biology have enabled the design of aggregation inhibitors, receptor-selective neuropeptide analogues, and cell-penetrating or brain-targeted peptide conjugates that modulate key pathways, including proteostasis, insulin and incretin signaling, neurotrophic support, and microglial activation

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[17] However, no large-scale, controlled trials have evaluated the efficacy or safety of ALA for pregnant patients, and thus there is insufficient evidence to consider it definitively safe

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Interventions using specific dietary components and engineered probiotics show promise in restoring gut-liver homeostasis and mitigating cadmium-induced damage