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Although several psychological factors (for example, deficit in impulse control) are known to play a major role in the pathophysiology of obesity 248 , we here raise the issue of disparity in the provision of psychiatric care for the treatment of obesity compared with other eating disorders, which are predominantly treated by psychiatrists, and advocate for the importance of a multidisciplinary, integrated approach to weight management

GLP-1 Binding The EM structure of the GLP-1 apo receptor (i.e., receptor in the absence of any ligand), shows that the N-terminal domain adopts a closed or inactive conformation, where a cap-like structure blocks access to the peptide binding ( PDB ID 6ln2, Wu et al., 2020, Figure 4a)