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Therefore, our laboratory developed the MZ-, JI-, and MR-series of GH-RH agonists with enhanced GH-releasing potency both in vitro and in vivo 53,62

The recommended washout period differs by product: the UK Summary of Product Characteristics (SmPC) for semaglutide (Wegovy) advises stopping treatment at least two months before a planned pregnancy, whilst the SmPC for tirzepatide (Mounjaro) advises stopping at least one month before

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Black vertical lines indicate median values which are also expressed numerically in each figure (on the right-hand side)