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Yes, B12 injections are generally considered very safe with minimal side effects
Here's the TL;DR on vitamin timing: while there is no official medical advice dictating that you should take vitamin supplements at a specific time of day to improve their efficiency, there is quite a lot of research showing that avoiding some vitamin supplements at particular times (or more accurately, with particular meals) can improve absorption, or that taking some vitamins alongside food can reduce the risk of adverse side effects
A taper, resistance training, 0.7 g/lb protein, and clinical follow-up reduce the regain risk but dont guarantee weight maintenance
The trial enrolled 809 adults with obesity and at least one comorbidity, with a mean baseline body weight of 114.2 kg
78 KashaniZ.PakzadR.FakariF.HaghparastM.AbdiF.KianiZ.et al (2023)
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