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However, the scientific evidence does not support the idea that vitamin B12 injections or supplementation directly lead to weight gain

With the rise of injectables like Wegovy and Zepbound, more people than ever are turning to these treatments to support their weight loss goals

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Levels drop because of two reasons: our bodies produce less as we age, and enzymes like CD38 (which increases with inflammation) actively destroy NAD+

It also helps create those beneficial compounds that improve insulin sensitivity