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Glucagon-like peptide-1 receptor agonists gained approval as drugs to treat diabetes and obesity starting in the 2000s

The mean reduction in body weight from baseline to week 104 was significantly higher in the semaglutide group (n = 152) compared to the placebo group (n = 152), with an estimated treatment difference of -12.6 percentage points (95% confidence interval: -15.3 to -9.8

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Just do not inject into a thigh muscle immediately after a leg workout