Has the vial been stored properly
This includes individuals with: Diagnosed MASLD or MASH, where GLP-1 therapy may offer therapeutic benefits but requires monitoring Chronic viral hepatitis (hepatitis B or C), particularly if transaminases are elevated Autoimmune hepatitis or other inflammatory liver conditions Cirrhosis or advanced fibrosis, where specialist consultation may be appropriate despite generally not requiring dose adjustment History of drug-induced liver injury from other agents For these patients, baseline comprehensive liver assessmentincluding liver enzymes, synthetic function tests (albumin, INR), and potentially imaging or non-invasive fibrosis markers (such as FIB-4 or ELF)helps establish a reference point for monitoring treatment effects
Differences across groups were tested using ANOVA with a Tukey post hoc test when more than two experimental groups were analysed and using Students t-test when only two experimental groups were compared
Results: Twelve PwT1D (8/12, 66.7% women) with mean (SD) age 65 (2) years, diabetes duration 36 (12) years, BMI 28.1 (4.1) kg/m 2 , HbA1c 7.5 (0.9) % (58 [10] mmol/mol) and time in range 68 (17) % were analysed
Mazdutide is currently only available in China under the brand name Xinermei
