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Eli Lilly has not publicly announced pediatric clinical trials for orforglipron as of early 2026, but the commercial and clinical logic for eventual pediatric development is strong

Yet, for others, levels barely improve

Clinical trials demonstrate that patients treated with Zepbound experience modest but meaningful blood pressure reductions alongside substantial weight loss

While it does not directly speed up metabolism, it plays a significant role in weight loss through appetite suppression and improved insulin sensitivity