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LHCGR Binding and Biased Agonism Research using BRET and FRET technologies in living cells confirmed that hCG and LH differentially promote cell responses mediated by the LHCGR revealing divergences in potency, efficacy, and kinetics

10.1038/bjp.2008.153 149 VingrenJ

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For example, Motus (oral) by Tonum reported around 10.4% average weight loss in human clinical trials over six months which is substantial for an oral supplement

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