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According to the SURE (SemaglUtide Real-World Evidence) program analysis, about 16% of people experience an increased heart rate after two years on Ozempic, compared to 11% of people who were not on Ozempic in the same time frame, says Erika Gray, PharmD, founder of MytoolBox Genomics in San Francisco, California

Healthcare providers may recommend microdosing semaglutide and tirzepatide (Mounjaro and Zepbound) off-label

These pharmacies typically assign more conservative BUDs because they may not have the analytical resources to conduct extended stability testing on every formulation they compound

Novo is expected to release results from its 5-year SELECT trial looking into the health impact of its injectable drug, particularly around heart disease, later this year

One longer-term study followed people taking semaglutide for 208 weeks (about 4 years)