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Immunofluorescence analysis of PC-12 cells using Glutathione Synthetase Rabbit pAb at dilution of 1:100

For those with contraindications to, or personal preferences against, using pharmacologic therapies, the following natural supplements have evidence to support their use in managing perimenopausal symptoms: Phytoestrogens , found in soy, beans, flax seeds, and cruciferous vegetables, are plant compounds that may support the reduction of menopausal symptoms (5)

The National Institutes of Health in the US have followed suit in prioritizing the development and use of human-relevant testing methods by stating that projects only encompassing animal studies will no longer be funded (219)

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