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The retrospective cohort study (conducted exclusively by neuro-ophthalmologists with expertise in diagnosing NAION) found that diabetic patients prescribed semaglutide faced a 4.28-fold increased risk of developing NAION compared to those on other diabetes medications while even more concerning, overweight or obese patients using semaglutide for weight loss experienced a staggering 7.64-fold increased risk

Tirzepatide is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for type 2 diabetes management under the brand name Mounjaro and for chronic weight management as Zepbound

Autism 2009;13:123

High-Fat Foods (especially saturated and trans fats): While healthy fats are beneficial, its best to limit foods high in saturated and trans fats, such as fried foods, fatty cuts of meat, and many processed snacks

Quick Answer: Tirzepatide does not directly cause gallstones, but its rapid weight loss effects increase gallstone risk, with clinical trials showing cholelithiasis in 2.5% of treated patients versus 1.0% on placebo