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SARS-CoV-2 Invasion with Subsequent Brain Injuries Like SARS-CoV and the Middle East Respiratory Syndrome Coronavirus, 33 SARS-CoV-2 can also invade and spread throughout the brain

Sirtuins are known to influence the body's response to oxidative stress and inflammation, and their dysregulation could lead to increased oxidative damage and reduced ATP production (Sara et al., 2021), further exacerbating symptoms of fatigue and metabolic dysfunction