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In the thrid section, experiments encompassed immunofluorescence staining, western blot, brain edema measurement, TEM and Elisa assay each utilized 36 mice (6 mice each from Slc25a39 fl/fl + Sham group, Slc25a39 fl/fl + TBI group, Slc25a39 fl/fl + TBI + rFGF21 group, Slc25a39 CKO + Sham group, Slc25a39 CKO + TBI group, and Slc25a39CKO + TBI + rFGF21 group)

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