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P.CaldanaC.MehrniaM.et al (2010)

(73) believed that the important mechanism for NOR to exert anti-RA characteristics might be to prevent the release of IL-6 from FLSs, and its mechanism might be related to the inhibition of PKC/MAPKs/p65/cAMP response element-binding protein (CREB) pathway

Moreover, these anti-inflammatory properties also extend to the neuro-ophthalmic circuit, which is embryonically related to the central nervous system and is thus similarly afflicted by pathologies driven by inflammation

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The procedure is performed by surgeons who have advanced surgical training in this specialty area