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In addition to being a GLP-1 agonist, Tirzepatide also mimics the effects of glucose-dependent insulinotropic polypeptide (GIP)

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Retatrutide has Phase 2 (Jastreboff et al., NEJM 2023, PMID 37366315) and Phase 3 (TRIUMPH-4, Bays et al., NEJM 2025, PMID 41090431) data

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