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From a pathophysiological viewpoint substances counteracting insulin resistance appear to be the first choice also in acromegaly (53)

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The conflicting findings regarding M1 and M2 macrophage polarization suggest that the effects of NAC may be context-dependent, influenced by factors such as concentration, cell type, and specific microenvironmental conditions

Common side effects: Nausea, diarrhoea, abdominal discomfort: usually settle within a few weeks if dose is built up gradually