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The compound exhibits a notably long half-life of approximately 9 days (220 hours) and is metabolized primarily by cytochrome P450 3A4 to its active metabolite M1 (NS2360), which has an even longer half-life of 16 days (374 hours)
Anyone under 21 should avoid REGEN unless under medical supervision, as peptide effects on developing bodies are not well studied
Since senescent cells may release a senescence-associated secretory phenotype, the authors suggest that lowering the senescent cell burden may reduce pro-fibrotic signaling in the surrounding cells
This can reduce anxiety, improve focus, and prevent sensory overload that might cause distress or behavioral challenges
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