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ROS induces the activity of apoptosis-related enzymes, causing damage to the podocytes and promoting the proliferation of fibrotic cells to induce the synthesis of ECM (Tong et al., 2017)

That fragment acts on a target the same Washington State group helped pin down: the so-called AT4 receptor, which was identified as IRAP, insulin-regulated aminopeptidase, an enzyme rather than a classical receptor (Albiston et al., J Biol Chem 2001)

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In HeLa tumor-bearing mice, drug cytotoxicity was significantly increased and tumor hypoxia was enhanced

The IV drip of this potent antioxidant has become one of the hottest wellness treatments in recent yearsespecially among those looking to detox and boost immunity