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(2021) Homocysteine, vitamin B status and MTHFR polymorphisms in Italian infertile women, Gynecology and reproductive biology, Vol

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194 Obesity can induce systemic metabolic disruptions within the body, leading to dyslipidemia, hypercholesterolemia, insulin resistance, alterations in hormone levels, and changes in the baseline inflammation status

In order to set the system in motion, a stimulus must drive a physiological parameter beyond its normal range (that is, beyond homeostasis)