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Published in the Journal of Clinical Investigation Insight , the research found that inconsistent use of GLP-1 drugs may reduce their effectiveness when patients resume treatment

A potent endogenous antioxidant, glutathione is essential for the liver's phase I and phase II detoxification.* However, negative lifestyle issues and adverse conditions that affect liver health can result in a decreased amount of glutathione in the liver

Of course, you can also consider using a non-hormonal option, like the copper IUD or condoms, if you dont want to worry about drug interactions (condoms are also the only method that protects against STIs)

10.3390/ph13030046 Pharmaceuticals (Basel, Switzerland) 58 SimunkovaM.AlwaselS.AlhazzaI.JomovaK.KollarV.RuskoM.et al (2019)

10.1016/j.pharep.2017.10.003 52 GanX.ZhaoJ.ChenY.LiY.XuanB.GuM.et al (2022)