In the model proposed by Lee, homocysteine is shunted away from the methionine synthesis pathway and toward the GSH synthesis pathway, creating a relative deficiency of methyl donors in order to keep up with increased demand for the glutathione needed for POP conjugation ( Fig 3 )
TBARS, thiobarbituric acid-reacting substances
GLPs demonstrates defensive impacts against diabetes and its associated complications including nephropathy, hepatopathy, cardiomyopathy, refractory wound healing, neuropathy, retinopathy, and erectile dysfunction--through mechanisms involving oxidative stress modulation, glucolipid metabolism regulation, anti-apoptosis, islet cells repair, and the gut microbiota remodeling
Grilling and frying can increase histamine production in foods, so opt for alternative cooking methods such as steaming, poaching, baking, boiling, slow or pressure cooking, or microwaving
Once a GSH molecule de-activates a free radical it becomes oxidized