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When the same research group tested oral formulations, they required 3-5 times higher doses to achieve comparable therapeutic effects

The FDA classifies substances intended for administration to humans without approved status as adulterated or misbranded drugs under federal law, meaning commercial products sold as injectable BPC-157 for human use violate federal regulations

Moreover, in a lung cancer mouse model, the peptide N-acetylglucosaminyltransferase 3 suppressed AKT phosphorylation triggered by c-MET, leading to decreased synthesis of the chemokine CXCL3, which is essential for MDSC attraction [82]

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