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3.1 Alternative nutrient-sensing mechanisms Some nutrients stimulate intestinal hormone secretion independent of taste receptors, via pathways involving other GPCR or nutrient transporters (95, 96): Stomach: Calcium-sensing receptor (CaSR) and GPRC6A detect a broad range of amino acids and calcium, promoting gastrin and somatostatin release (89, 97)
Calibrates program addresses this by targeting the underlying causes of inflammation, such as excess weight, poor diet, and insulin resistance
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Enhances cardiovascular health, exercise capacity, eating habits, sleep, and stress management
doi: 10.1056/NEJMoa1203858 264 SattarNMcGuireDKPavoIWeerakkodyGJNishiyamaHWieseRJet al
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