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While semaglutide pharmacokinetics are not significantly altered in patients with hepatic impairment, the medication has not been extensively studied in patients with severe hepatic dysfunction

McAlpine, Fiona E.., Jae-Kyung

Monolayers were then washed, equilibrated for 5 min at 37C in 100 l KHB-BSA for subsequent recording of fluorescence as an index of intracellular [Ca 2+ ] ([Ca 2+ ] i ) using a microplate reader (NOVOstar