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Aiming for a steady baseline intake of 64 to 80 ounces of fluids daily is a reasonable starting point for many adults, though individual needs vary based on body size and activity levels

Severe or Persistent Nausea and Vomiting: If nausea becomes debilitating, prevents you from staying hydrated, or leads to significant weight loss beyond what is intended, its time to speak with your licensed healthcare provider

Studies in pregnant rats have shown embryofetal mortality, structural abnormalities, and alterations to growth when administered during organogenesis at maternal exposures below the maximum recommended human dose (MRHD)

Clinical trials suggest that Zepbound can lead to a weight reduction of 15-20%, depending on the dosage and patient adherence to lifestyle adjustments

However, some peptides, such as semaglutide and tirzepatide, are FDA-approved for weight loss under brand names Wegovy and Zepbound, respectively