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Moreover, Ras induces Ras-related C3 botulinum toxin substrate 1 (Rac1), which in turn leads to further stimulation of p38 MAPK and JNK (Trusolino et al., 2010)

These effects, when present, are typically manageable and resolve with continued use or dose adjustment

This is thought to occur through modulation of key signaling pathways like NF-B

What is AOD9604's regulatory status

J Physiol Paris 93:479485 Sikiric P, Seiwerth S, Brcic L, Blagaic AB, Zoricic I, Sever M, Klicek R, Radic B, Keller N, Sipos K et al (2006) Stable gastric pentadecapeptide BPC 157 in trials for inflammatory bowel disease (PL-10, PLD-116, PL 14736, Pliva, Croatia)