labial melanotic macule laser removal Mystery behind and oral macules: Clinical, dermoscopic and pathological aspects of Laugier-Hunziker syndrome Oral melanotic macula on the

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When the copper ion sits correctly chelated within the peptide structure, it absorbs light wavelengths that leave the characteristic blue visible to your eye

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Digestion was carried out overnight by adding two aliquots of trypsin (first at a 1:40 w/w ratio of trypsin and second at a 1:50 w/w ratio, with a 4-hour interval between additions) at 37 C with agitation (800 rpm)

Nature 486 , 554558 (2012)