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The spectrum ranges from simple steatosis (fat accumulation without significant inflammation) to nonalcoholic steatohepatitis (NASH), which involves inflammation and hepatocyte injury that can progress to fibrosis, cirrhosis, and hepatocellular carcinoma

14 Almost half of the participants on the 12 mg dose lost 30% or more of their body weight, a level usually associated with weight-loss surgery

It works by reducing the absorption of dietary fat, helping promote weight loss when combined with a reduced-calorie, low-fat diet and regular physical activity

Brain and blood metabolite signatures of pathology and progression in Alzheimer disease: a targeted metabolomics study