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GPX4 is a selenium protein expressed by cells of various organs, and its synthesis and activity are affected by selenium and GSH levels [78, 79]

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This pathway can control the expression of PEBP1, ERK1/2, GPX4, FTH1, ACSL4, and COX2, thereby enhancing the function of hippocampal astrocytes and microglial cells in CUMS model mice (Yang et al., 2023) (Table 1)