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Understanding Its Biological Mechanisms One of the most common questions among researchers is How does BPC-157 work? Unlike many experimental peptides that target a single receptor or signaling pathway, BPC-157 appears to influence several interconnected biological processes

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Matzaras R, Nikopoulou A, Protonotariou E, Christaki E

Epub 2021 Sep 28

The combination of the lysosome disruptor siramesine and the tyrosine kinase inhibitor lapatinib increased the expression of TF and reduced the expression of FPN1 in breast cancer cells, thereby promoting iron overload in the lysosome and ultimately inducing ferroptosis (Ma et al., 2016)