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In murine models, Spinacia oleracea -derived CQDs showed safe distribution at concentrations up to 100 g/mL with no histological organ damage, whereas higher doses elicited mild liver lymphocyte infiltration [154]

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I-FAPB is a protein present in differentiated enterocytes, and damage to the epithelial layer results in this protein being released from cells hence, it is considered an indicator of epithelial damage [74]

EpCAM knockdown alters microRNA expression in retinoblastoma-functional implication of EpCAM regulated miRNA in tumor progression