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3e), indicating destabilization of the polypeptide chain upon enzyme reduction

The further enhanced effects of these second-generation compounds on lowering blood glucose, reducing weight, and protecting the heart and kidneys, is now encouraging further clinical development and points to many possible novel combinations of medicines in the future

Owing to the shared pathophysiological mechanism and close bidirectional impact between NAFLD and T2DM, antidiabetic medications have been evaluated as treatments for NAFLD

We may consider information from interested parties for future rulemaking