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The pancreatic cancer question is harder

10.3390/nu12051351 Nutrients

In a 2-year trial with semaglutide 0.5 mg and 1 mg once-weekly injection in adult patients with type 2 diabetes and high cardiovascular risk, diabetic retinopathy complications (which was a 4-component adjudicated endpoint) occurred in patients treated with semaglutide injection (3.0%) compared to placebo (1.8%)

Adequate protein, hydration, and micronutrient supplementation usually resolve this

Several factors influence early weight loss outcomes: Starting dose and titration schedule : Lower initial doses produce less pronounced early weight reduction but are necessary to improve tolerability