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These varied activities make GSH an attractive target for a more reductionist approach to the prevention and management of many conditions of interest to surgeons

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For example, in one clinical trial, hypertensive TT subjects taking 1.6 mg/day of riboflavin (in addition to normal antihypertensive medication) over 16 weeks experienced an average decrease of 5.6 mm/Hg in systolic blood pressure compared to those taking a placebo

Identified publications were reviewed for relevant data and were included in the review if appropriate