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Previous stroke A documented history of ischemic or hemorrhagic stroke qualifies

The combination of the very high price of these drugs typically about $1,000 per month per patient plus a relatively large number of patients who may benefit from them can result in a substantial net new cost to a health plan, potentially more than many employers or the employees who share the cost of coverage can afford

Most significant side effects, like nausea, tend to diminish after the first few weeks of treatment in clinical trials

It weaponizes employee sentiment against the employer's treasury

They are not in the same league on results, and berberine is not a replacement for a prescribed medicine